Open Letter
to Dr June Raine,
Chief Executive, MHRA

Dr Tess Lawrie MBBCh, DFSRH, PhD

Tess, as director of E-BMC Ltd, is committed to improving the quality of healthcare through rigorous research. Her range of research expertise, based on research experience in both developing and developed countries, uniquely positions her to evaluate and design research for a variety of healthcare settings. Tess is a frequent member of technical teams responsible for developing international guidelines. Her peer-reviewed publications have received in excess of 3000 citations and her ResearchGate score is among the top 5% of ResearchGate members.

Our collaboration with Dr. Tess Lawrie of the Evidence-based Medicine Consultancy led to her writing an open letter to Dr June Raine, Chief Executive of the Medicines and Healthcare products Regulatory Agency (MHRA).

The letter presents the initial findings of our joint analysis of the very limited information that the MHRA weekly Yellow Card scheme reports provide.

The letter also calls for an immediate halt of the COVID-19 vaccine rollout while further, more detailed, analysis of the Yellow Card reports data is made.

Key Findings and Concerns

In her letter, Dr Lawrie explains that the true prevalence of certain reactions up to and including death had apparently gone unnoticed because similar conditions had been classified in different ways.

For example, the MHRA report that there have been 24 fatalities from brain clots and bleeds. However our analysis showed that there were an additional 832 fatalities of this nature that had mainly been classified under nervous system, respiratory system or cardiac conditions.

Similarly, with immune system reactions, the “headline” MHRA figure is 4 fatalities of this nature, but again by searching the reports for keywords relating to the immune system, we unearthed an additional 167 deaths.

The key issue is that as there are so many different ways of categorising identical or similar conditions, the significance and frequency of certain reactions is missed. Twenty seemingly different categories each with a handful of reports in each does not raise concerns whereas one category with all those reports in shows a very different, and more worrying, picture.

Read the full letter